Thursday, March 27, 2008

Mitochondrial dysfunction in regressive autism

Just wanted to post these 'ARTICLE MAJOR POINTS' from David Kirby's Huffington Post entry. While I don't think that 'it is as simple as the genetic susceptibility for mitochondrial dysfunction in autism is inherited through the father, not the mother' (I believe that BOTH parents contribute to the genetic susceptibility), a lot of what is listed is a very close match to the things Dr. Amy Yasko has been looking into (and actively addressing with her protocol) for years!!!

ARTICLE MAJOR POINTS:

• Up to 1 in 50 children (2%) may have a genetic mutation that puts them at risk for mitochondrial dysfunction.

• Up to 20% of all children with autism may have an underlying mitochondrial dysfunction

• Children with mitochondrial dysfunction are more likely to regress into autism between the ages 1 and 2 years, if they have fever or illness from viral infections or vaccines.

• The CDC is aware of this difficult situation and is taking measures immediately to address the current national vaccine schedule.

• The genetic susceptibility for mitochondrial dysfunction in autism is inherited through the father, not the mother, as previously thought, and is not rare at all.

• The DNA mutation might not be enough in itself to confer cellular dysfunction, and many doctors believe there is an environmental trigger as well.

• They note that thimerosal, mercury, aluminum, pollution, pesticides, medicines and prenatal alcohol exposure have all been shown to damage mitochondria.

• Other doctors believe that a corn-byproduct based diet in America has put children in a constant inflammatory state, thus making the DNA mutation more pathogenic.

• While some children with mitochondrial dysfunction regress into autism following fever and illness from a viral infection; other kids, like Hannah Poling, clearly regress following a reaction to vaccines.

• The exact percentage of people with vaccine induced autism is unknown. But even a 1% rate could mean 10,000 Americans with vaccine related autism, at a cost of many billions of dollars for lifetime care.

• Some changes in the vaccine schedule will almost surely be made. The most difficult decision is how and when to vaccinate children with proven mitochondrial dysfunction.

• This hot topic will be the subject of a daylong meeting of the HHS National Vaccine Advisory Committee's Vaccine Safety Working Group, in Washington, DC on April 11.


I'd be lying if I said I didn't feel a little 'vindicated' by all of this..

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